BDBM267432 2-(5-tert-Butyl-4-chloro-2-methyl-2H-pyrazol-3-yl)-5-(2- trifluoromethyl-phenyl)-1H-imidazo[4,5-b]pyridine ::US9718820, Compound 32

SMILES Cn1nc(c(Cl)c1-c1nc2ccc(nc2[nH]1)-c1ccccc1C(F)(F)F)C(C)(C)C

InChI Key InChIKey=FEAKTZMJAPSQLP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 267432   

TargetTransient receptor potential M8 protein(Dog)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM267432(2-(5-tert-Butyl-4-chloro-2-methyl-2H-pyrazol-3-yl)...)
Affinity DataIC50:  7.60nMT: 25°CAssay Description:HEK293 cells stably expressing canine TRPM8 were routinely grown as monolayers in Dulbecco's minimum essential medium supplemented with 10% FBS, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent