BDBM267441 US9718822, 24::US9750744, Example 24::US9902741, Example 24

SMILES Fc1ccc2OCCCNCc3cnn4ccc(nc34)N3CCC[C@@H]3c2c1

InChI Key InChIKey=OAERZRAEDKYULV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 267441   

TargetHigh affinity nerve growth factor receptor(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 267441BDBM267441(US9718822, 24 | US9750744, Example 24 | US9902741,...)
Affinity DataIC50: 1.55E+3nMAssay Description:An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 267441BDBM267441(US9718822, 24 | US9750744, Example 24 | US9902741,...)
Affinity DataIC50: 1.55E+3nMAssay Description:An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors Immulon 4HBX 384-well microtiter p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Array Biopharma

US Patent
LigandChemical structure of BindingDB Monomer ID 267441BDBM267441(US9718822, 24 | US9750744, Example 24 | US9902741,...)
Affinity DataIC50: 1.55E+3nMpH: 7.5Assay Description:An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent