BDBM2677 US8507479, 140::US8507479, 80::US8541408, 80

SMILES CCSc1cnc(C(=O)Nc2cccc([C@]3(C)CCSC(N)=N3)c2)cn1

InChI Key InChIKey=BMAIEHAATLKYFE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2677   

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 2677BDBM2677(US8507479, 140 | US8541408, 80 | US8507479, 80)
Affinity DataIC50: 70nMAssay Description:Beta-Secretase inhibition assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2013
Entry Details
US Patent

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 2677BDBM2677(US8507479, 140 | US8541408, 80 | US8507479, 80)
Affinity DataIC50: 70nMpH: 7.0Assay Description:Inhibition assay using human BACE-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2013
Entry Details
US Patent