BDBM26811 CHEMBL485202::N-[2-benzamido-1-(2-carbamoylethyl)-2,3-dihydro-1H-1,3-benzodiazol-5-yl]-N-methylbenzamide::acylated 2-aminobenzimidazole, 1

SMILES CN(C(=O)c1ccccc1)c1ccc2n(CCC(N)=O)c(NC(=O)c3ccccc3)nc2c1

InChI Key InChIKey=NWUSHDACDTZXCD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 26811   

TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26811(N-[2-benzamido-1-(2-carbamoylethyl)-2,3-dihydro-1H...)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant ITK by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26811(N-[2-benzamido-1-(2-carbamoylethyl)-2,3-dihydro-1H...)
Affinity DataIC50: 120nMAssay Description:Inhibition of IRKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26811(N-[2-benzamido-1-(2-carbamoylethyl)-2,3-dihydro-1H...)
Affinity DataIC50: 180nMpH: 7.0 T: 2°CAssay Description:Kinase is purified as a GST-fusion protein. The kinase activity is measured using DELFIA which utilizes europium chelate-labeled anti-phosphotyrosine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Johnson & Johnson

Curated by ChEMBL
LigandPNGBDBM26811(N-[2-benzamido-1-(2-carbamoylethyl)-2,3-dihydro-1H...)
Affinity DataIC50: 560nMAssay Description:Kinase is purified as a GST-fusion protein. The kinase activity is measured using DELFIA which utilizes europium chelate-labeled anti-phosphotyrosine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2009
Entry Details Article
PubMed