BDBM268431 N-(7-((1-methylcyclohexyl)methoxy)-6-vinyl-[1,2,4]-triazolo[4,3-a]pyridin-3-yl)methanesulfonamide::US9550775, 62::US9550775, 7

SMILES CC1(COc2cc3nnc(NS(C)(=O)=O)n3cc2C=C)CCCCC1

InChI Key InChIKey=BCMJWEHACAZZLH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 268431   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268431BDBM268431(N-(7-((1-methylcyclohexyl)methoxy)-6-vinyl-[1,2,4]...)
Affinity DataIC50: 65nMpH: 7.2Assay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268431BDBM268431(N-(7-((1-methylcyclohexyl)methoxy)-6-vinyl-[1,2,4]...)
Affinity DataIC50: 65.3nMpH: 7.2Assay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent