BDBM268443 N-(7-(adamantan-1-ylmethoxy)-6-bromo-[1,2,4]triazolo[4,3-a]-pyridin-3-yl)morpholine-4-sulfonamide)::US9550775, 64::US9550775, 9

SMILES O=S(=O)(Nc1nnc2cc(OCC34CC5CC(CC(C5)C3)C4)c(Br)cn12)N1CCOCC1

InChI Key InChIKey=BLBHTWCDIJCZNG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 268443   

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268443BDBM268443(N-(7-(adamantan-1-ylmethoxy)-6-bromo-[1,2,4]triazo...)
Affinity DataIC50: 206nMpH: 7.2Assay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent

TargetSodium channel protein type 9 subunit alpha(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 268443BDBM268443(N-(7-(adamantan-1-ylmethoxy)-6-bromo-[1,2,4]triazo...)
Affinity DataIC50: 210nMpH: 7.2Assay Description:The following patch voltage clamp electrophysiology studies were performed on representative compounds of the invention using human embryonic kidney ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2018
Entry Details
US Patent