BDBM269436 (E)-3-(4-((6-hydroxy-2- (6-methoxy-2- (trifluoromethyl)pyridin- 3-yl)benzo[b]thiophen- 3-yl)oxy)phenyl)acrylic acid::US10058534, 91

SMILES COc1ccc(-c2sc3cc(O)ccc3c2Oc2ccc(\C=C\C(O)=O)cc2)c(n1)C(F)(F)F

InChI Key InChIKey=MEBDKRSYJVAHQF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 269436   

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 269436BDBM269436((E)-3-(4-((6-hydroxy-2- (6-methoxy-2- (trifluorome...)
Affinity DataIC50: 23nMpH: 5.1 T: 2°CAssay Description:The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent