BDBM269450 (E)-2-(2- isopropylphenyl)-3-(4- (2-(5-methyl-4H-1,2,4- triazol-3- yl)vinyl)phenoxy)benzo [b]thiophen-6-ol::US10058534, 105

SMILES CC(C)c1ccccc1-c1sc2cc(O)ccc2c1Oc1ccc(\C=C\c2nnc(C)[nH]2)cc1

InChI Key InChIKey=DWKXPLMQTDGQRW-XNTDXEJSSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 269450   

TargetEstrogen receptor(Human)
Novartis

US Patent
LigandPNGBDBM269450((E)-2-(2- isopropylphenyl)-3-(4- (2-(5-methyl-4H-1...)
Affinity DataIC50:  1.10nMpH: 7.4 T: 25°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetEstrogen receptor(Human)
Novartis

US Patent
LigandPNGBDBM269450((E)-2-(2- isopropylphenyl)-3-(4- (2-(5-methyl-4H-1...)
Affinity DataIC50:  14nMpH: 5.1 T: 37°CAssay Description:The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent