BDBM27054 Macrocyclic Peptidomimetic, 22::tert-butyl N-[(3S,13S,16S,17R,19S)-18,18-dimethyl-2,15-dioxo-13-[(prop-2-en-1-ylcarbamoyl)carbonyl]-5-oxa-1,14-diazatricyclo[14.4.0.0^{17,19}]icosan-3-yl]carbamate

SMILES CC(C)(C)OC(=O)N[C@H]1COCCCCCCC[C@H](NC(=O)[C@@H]2[C@@H]3[C@H](CN2C1=O)C3(C)C)C(=O)C(=O)NCC=C

InChI Key InChIKey=ZHURZEVUEVEVIK-YFNVTMOMSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27054   

TargetGenome polyprotein(HCV)
Schering-Plough Research Institute

LigandPNGBDBM27054(Macrocyclic Peptidomimetic, 22 | tert-butyl N-[(3S...)
Affinity DataKi:  150nM ΔG°:  -9.46kcal/molepH: 6.5 T: 30°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed