BDBM271154 4-[(RS,SR)-2,3-dimethylmorpholin-4-yl]-7-(2-fluorobenzenesulfonyl)-2-methyl-5H-pyrrolo[3,2-d]pyrimidin-6-amine::US10059713, Example 275

SMILES Cc1nc(N2CCO[C@H](C)[C@@H]2C)c2[nH]c(N)c(S(=O)(=O)c3ccccc3F)c2n1

InChI Key InChIKey=AZEKYSPKUXGNPX-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 271154   

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271154BDBM271154(4-[(RS,SR)-2,3-dimethylmorpholin-4-yl]-7-(2-fluoro...)
Affinity DataEC50:  8nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent