BDBM271162 7-(2-fluoro-4-methoxybenzenesulfonyl)-2-methyl-4-[(2S)-2-(trifluoromethyl)morpholin-4-yl]-5H-pyrrolo[3,2-d]pyrimidin-6-amine::US10059713, Example 282

SMILES COc1ccc(S(=O)(=O)c2c(N)[nH]c3c(N4CCO[C@H](C(F)(F)F)C4)nc(C)nc23)c(F)c1

InChI Key InChIKey=HCVZDBSNADMNCS-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 271162   

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271162BDBM271162(7-(2-fluoro-4-methoxybenzenesulfonyl)-2-methyl-4-[...)
Affinity DataEC50:  1nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
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Date in BDB:
12/11/2018
Entry Details
US Patent