BDBM271177 7-(4-chloro-2-fluorobenzenesulfonyl)-2-methyl-4-[(2R)-2-(trifluoromethyl)morpholin-4-yl]-5H-pyrrolo[3,2-d]pyrimidin-6-amine::US10059713, Example 297

SMILES Cc1nc(N2CCO[C@@H](C(F)(F)F)C2)c2[nH]c(N)c(S(=O)(=O)c3ccc(Cl)cc3F)c2n1

InChI Key InChIKey=PYTJUWVZOWTLEX-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 271177   

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 271177BDBM271177(7-(4-chloro-2-fluorobenzenesulfonyl)-2-methyl-4-[(...)
Affinity DataEC50:  2nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
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Date in BDB:
12/11/2018
Entry Details
US Patent