BDBM271182 7-(2-fluorobenzenesulfonyl)-2-(methylsulfanyl)-4-[2-(trifluoromethyl)morpholin-4-yl]-5H-pyrrolo[3,2-d]pyrimidin-6-amine::US10059713, Example 301

SMILES CSc1nc(N2CCOC(C2)C(F)(F)F)c2[nH]c(N)c(c2n1)S(=O)(=O)c1ccccc1F

InChI Key InChIKey=INNFWAIBUHUWLL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 271182   

TargetFree fatty acid receptor 2(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM271182(7-(2-fluorobenzenesulfonyl)-2-(methylsulfanyl)-4-[...)
Affinity DataEC50:  2nMAssay Description:GPR43 agonist/PAM activity was determined by measuring changes in intracellular calcium levels using a Ca2+ sensitive fluorescent dye. The changes in...More data for this Ligand-Target Pair
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Date in BDB:
12/11/2018
Entry Details
US Patent