BDBM271194 US10059720, Example 9::US10975091, Example 9

SMILES N[C@@H](CCC1CCC1)[C@](O)(Cc1cc(OCCC2CC2)ccn1)C(O)=O

InChI Key InChIKey=UAKRQQPFTAGJAK-AZUAARDMSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 271194   

TargetLeucyl-cystinyl aminopeptidase(Rattus norvegicus)
Astellas Pharma

US Patent
LigandPNGBDBM271194(US10059720, Example 9 | US10975091, Example 9)
Affinity DataIC50:  1.70nMAssay Description:Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP. The m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeucyl-cystinyl aminopeptidase(Homo sapiens (Human))
Astellas Pharma

US Patent
LigandPNGBDBM271194(US10059720, Example 9 | US10975091, Example 9)
Affinity DataIC50:  8.5nMAssay Description:hP-LAP: HEK293 cells forced to transiently express hP-LAP were prepared by lipofection, homogenized, and then subjected to ultracentrifugation at 100...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeucyl-cystinyl aminopeptidase(Rattus norvegicus)
Astellas Pharma

US Patent
LigandPNGBDBM271194(US10059720, Example 9 | US10975091, Example 9)
Affinity DataIC50:  1.70nMAssay Description:IRAP: Rat epididymal fat pads were homogenized and subjected to ultracentrifugation at 100,000×g for 30 minutes to obtain microsomes containing IRAP....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeucyl-cystinyl aminopeptidase(Homo sapiens (Human))
Astellas Pharma

US Patent
LigandPNGBDBM271194(US10059720, Example 9 | US10975091, Example 9)
Affinity DataIC50:  8.5nMAssay Description:HEK293 cells forced to transiently express hP-LAP (J Biol Chem 1996; 271: 56-61) were prepared by lipofection, homogenized, and then subjected to ult...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent