BDBM271440 4- (((3aR,5aR,5bR,7aR,9S, 11aR,11bR,13aS)-3a-(2- ((4- chlorobenzyl)amino)ethyl)- 1-isopropyl- 5a,5b,8,8,11a- pentamethyl- 3,3a,4,5,5a,5b,6,7,7a,8,9, 10,11,11a,11b,12,13,13a- octadecahydro-2H- cyclopenta[a]chrysen-9- yl)oxy)-2,2-dimethyl-4- oxobutanoic acid::US10064873, Example 66

SMILES CC(C)C1=C2[C@H]3CC[C@@H]4[C@@]5(C)CC[C@H](OC(=O)CC(C)(C)C(=O)O)C(C)(C)[C@@H]5CC[C@@]4(C)[C@]3(C)CC[C@@]2(CCNCc2ccc(Cl)cc2)CC1

InChI Key InChIKey=XLMBYDLHWRSBET-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 271440   

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Glaxosmithkline

US Patent
LigandChemical structure of BindingDB Monomer ID 271440BDBM271440(4- (((3aR,5aR,5bR,7aR,9S, 11aR,11bR,13aS)-3a-(2- (...)
Affinity DataEC50:  9.20nMAssay Description:Antiviral HIV activity and compound-induced cytotoxicity were measured in parallel by means of a propidium iodide based procedure in the human T-cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetEnvelope glycoprotein gp160 [V370A](Human immunodeficiency virus type 1)
Glaxosmithkline

US Patent
LigandChemical structure of BindingDB Monomer ID 271440BDBM271440(4- (((3aR,5aR,5bR,7aR,9S, 11aR,11bR,13aS)-3a-(2- (...)
Affinity DataEC50:  16.1nMAssay Description:Antiviral HIV activity and compound-induced cytotoxicity were measured in parallel by means of a propidium iodide based procedure in the human T-cell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent