BDBM271665 US10065941, Compound R-009::US9732060, Compound R-009

SMILES COc1cc(Oc2ccc(/N=c3\[nH]c(=O)n([C@@H](C)[C@@H](C)C(=O)O)c(=O)n3Cc3ccc(Cl)cc3)cc2)ccn1

InChI Key InChIKey=VHCWZTCHUCJFFM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 271665   

TargetP2X purinoceptor 3(Rat)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 271665BDBM271665(US10065941, Compound R-009 | US9732060, Compound R...)
Affinity DataIC50: 4nMAssay Description:Rat P2X3 receptor gene (GenBank accession number NM_031075) was expressed in C6BU-1 cell. The C6BU-1 cells were seeded in a 96-well microtiter plate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetP2X purinoceptor 3(Rat)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 271665BDBM271665(US10065941, Compound R-009 | US9732060, Compound R...)
Affinity DataIC50: 4nMAssay Description:Rat P2X3 receptor gene (GenBank accession number NM_031075) was expressed in C6BU-1 cell. The C6BU-1 cells were seeded in a 96-well microtiter plate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetP2X purinoceptor 3(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 271665BDBM271665(US10065941, Compound R-009 | US9732060, Compound R...)
Affinity DataIC50: 7nMpH: 7.5Assay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetP2X purinoceptor 3(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 271665BDBM271665(US10065941, Compound R-009 | US9732060, Compound R...)
Affinity DataIC50: 7nMAssay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent