BDBM271915 US10065941, Compound R-231::US9732060, Compound R-231

SMILES C[C@@H](Cn1c(=O)[nH]\c(=N/c2ccc(Oc3ccc4nccn4n3)cc2)n(Cc2ccc(Cl)cc2)c1=O)C(O)=O

InChI Key InChIKey=IIOUSTDGCVYDDS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 271915   

TargetP2X purinoceptor 3(Human)
Shionogi

US Patent
LigandPNGBDBM271915(US10065941, Compound R-231 | US9732060, Compound R...)
Affinity DataIC50: 5nMpH: 7.5Assay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetP2X purinoceptor 3(Human)
Shionogi

US Patent
LigandPNGBDBM271915(US10065941, Compound R-231 | US9732060, Compound R...)
Affinity DataIC50: 5nMAssay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent