BDBM27198 4-cyano-N-methyl-N-[(1R,2S,5S,6S,9R,12S,13R,16S)-6,7,13-trimethyl-7-azapentacyclo[10.8.0.0^{2,9}.0^{5,9}.0^{13,18}]icos-18-en-16-yl]benzamide::Conessine analogue, 12d

SMILES C[C@H]1[C@H]2CC[C@H]3[C@@H]4CC=C5C[C@@H](N(C)C(=O)c6ccc(C#N)cc6)CC[C@]5(C)[C@H]4CC[C@]23CN1C

InChI Key InChIKey=BGHMFFCWINSZMO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 27198   

TargetHistamine H3 receptor(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 27198BDBM27198(4-cyano-N-methyl-N-[(1R,2S,5S,6S,9R,12S,13R,16S)-6...)
Affinity DataKi:  39.8nM ΔG°:  -10.1kcal/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 27198BDBM27198(4-cyano-N-methyl-N-[(1R,2S,5S,6S,9R,12S,13R,16S)-6...)
Affinity DataKi:  195nMAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed