BDBM27202 Conessine analogue, 12h::methyl N-methyl-N-[(1R,2S,5S,6S,9R,12S,13R,16S)-6,7,13-trimethyl-7-azapentacyclo[10.8.0.0^{2,9}.0^{5,9}.0^{13,18}]icos-18-en-16-yl]carbamate

SMILES COC(=O)N(C)[C@H]1CC[C@@]2(C)C(=CC[C@H]3[C@@H]4CC[C@@H]5[C@H](C)N(C)C[C@@]54CC[C@@H]32)C1

InChI Key InChIKey=NFCMVAIYQLNHGO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 27202   

TargetHistamine H3 receptor(Human)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 27202BDBM27202(methyl N-methyl-N-[(1R,2S,5S,6S,9R,12S,13R,16S)-6,...)
Affinity DataKi:  60.3nM ΔG°:  -9.84kcal/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Abbott Laboratories

LigandChemical structure of BindingDB Monomer ID 27202BDBM27202(methyl N-methyl-N-[(1R,2S,5S,6S,9R,12S,13R,16S)-6,...)
Affinity DataKi:  257nMAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2009
Entry Details Article
PubMed