BDBM272037 US10065941, Compound I-258::US9732060, Compound I-258

SMILES CCc1ccc(Oc2ccc(/N=c3\[nH]c(=O)n(C[C@H](C)C(=O)O)c(=O)n3Cc3ccc(Cl)cc3)cc2)nc1

InChI Key InChIKey=FGNXQILEQVMHRB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 272037   

TargetP2X purinoceptor 3(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 272037BDBM272037(US10065941, Compound I-258 | US9732060, Compound I...)
Affinity DataIC50: 4nMAssay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2019
Entry Details
US Patent

TargetP2X purinoceptor 3(Human)
Shionogi

US Patent
LigandChemical structure of BindingDB Monomer ID 272037BDBM272037(US10065941, Compound I-258 | US9732060, Compound I...)
Affinity DataIC50: 4nMpH: 7.5Assay Description:Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683) was used. The cells were seeded ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent