BDBM273002 (S)-2-((1-(5-fluoro-6- (1H-1,2,4-triazol-5- yl)pyridin-3-yl)- 7,8,9,10-tetrahydro-6- oxa-2,10a- diazacycloocta[cd]inden-4- yl)oxy)propanamide::US10065970, Example 307::US10435414, Example 307
SMILES C[C@H](Oc1cc2OCCCCn3c(nc(c1)c23)-c1cnc(-c2ncn[nH]2)c(F)c1)C(N)=O
InChI Key InChIKey=SSCTZFIUWDNCSX-NSHDSACASA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 273002
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Genentech
US Patent
Genentech
US Patent
Affinity DataKi: <0.0200nMAssay Description:PI3K Binding assays are intended for determining the biochemical potency of small molecule PI3K inhibitors. The PI3K lipid kinase reaction is perform...More data for this Ligand-Target Pair