BDBM273079 (R)-N-benzyl-1-[6-(2,2-difluoroethyl)-5-(3-methyl-1,2,4-oxadiazol-5-yl)-7-oxo-6,7-dihydro[1,3]thiazolo[5,4-d]pyrimidin-2-yl]pyrrolidine-2-carboxamide::US10065972, Example 221
SMILES Cc1noc(n1)-c1nc2sc(nc2c(=O)n1CC(F)F)N1CCC[C@@H]1C(=O)NCc1ccccc1
InChI Key InChIKey=HLIJMZDGJGCTSG-CQSZACIVSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 273079
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
US Patent
Mitsubishi Tanabe Pharma
US Patent
Affinity DataIC50: 4.80nMpH: 8.0Assay Description:The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...More data for this Ligand-Target Pair