BDBM275045 5-Chloro-2-methoxy-N-(4-methyl-5-oxo-2,3,4,5-tetrahydropyrido[3,2-f][1,4]oxazepin-7-yl)benzenesulfonamide::US10221195, Example 1::US9879032, Example 1

SMILES COc1ccc(Cl)cc1S(=O)(=O)Nc1cnc2OCCN(C)C(=O)c2c1

InChI Key InChIKey=PRLGLYYIYIHPOU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 275045   

TargetAlkaline phosphatase, tissue-nonspecific isozyme(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM275045(5-Chloro-2-methoxy-N-(4-methyl-5-oxo-2,3,4,5-tetra...)
Affinity DataIC50:  6.30nMAssay Description:COS1 cells (DS Pharma Biomedical Co., Ltd.) were transfected with human TNAP (OriGene Technologies, Inc.) using Lipofectamine LTX & Plus reagent (Inv...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetAlkaline phosphatase, tissue-nonspecific isozyme(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM275045(5-Chloro-2-methoxy-N-(4-methyl-5-oxo-2,3,4,5-tetra...)
Affinity DataIC50:  6.30nMT: 25°CAssay Description:COS 1 cells (DS Pharma Biomedical Co., Ltd.) were transfected with human TNAP (OriGene Technologies, Inc.) using Lipofectamine LTX & Plus reagent (In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent