BDBM27542 4-(3-(piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one::4-[[3-(Piperazine-1-carbonyl)phenyl]methyl]-2H-phthalazin-1-one::4-{[3-(piperazin-1-ylcarbonyl)phenyl]methyl}-1,2-dihydrophthalazin-1-one::BMCL183942 Compound 2::CHEMBL201616::Piperazine analogue, 23
SMILES O=C(N1CCNCC1)c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1
InChI Key InChIKey=DDQGJTMUAYKRHB-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 27542
Affinity DataIC50: 2nMpH: 7.4 T: 22°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against PARP1More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of PARP-1 (unknown origin) assessed as incorporation of biotinylated poly ADP-ribose onto histone proteins by colorimetric analysis in pre...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.4 T: 22°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair