BDBM276039 2-(1-methylimidazol-4-yl)-4-(1H-triazol-4-yl)pyridine::US10071984, Example 1::US10174003, Example 1::US9896436, Example 1

SMILES Cn1cnc(-c2cc(-c3c[nH]nn3)ccn2)c1

InChI Key InChIKey=JMBGPAGLZBKRJX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 276039   

TargetHistone lysine demethylase PHF8(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 276039BDBM276039(2-(1-methylimidazol-4-yl)-4-(1H-triazol-4-yl)pyrid...)
Affinity DataIC50: 300nMAssay Description:PHF8 Assay: The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction condit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetLysine-specific demethylase 2B(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 276039BDBM276039(2-(1-methylimidazol-4-yl)-4-(1H-triazol-4-yl)pyrid...)
Affinity DataIC50: 300nMAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetIsoform 2 of Histone lysine demethylase PHF8 (2)(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 276039BDBM276039(2-(1-methylimidazol-4-yl)-4-(1H-triazol-4-yl)pyrid...)
Affinity DataIC50: 550nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent

TargetLysine-specific demethylase 2B(Human)
Celgene Quanticel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 276039BDBM276039(2-(1-methylimidazol-4-yl)-4-(1H-triazol-4-yl)pyrid...)
Affinity DataIC50: 550nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent