BDBM276474 2-[[1-[3-(Difluoromethyl)-4-fluoro-phenyl]triazol-4-yl]methoxy]-N-::US10071988, Example 413::US10233173, Example 413

SMILES COCC(=O)N1CCc2[nH]c3c(Cl)c(Cl)ccc3c2C1

InChI Key InChIKey=PJRNVVYBYALHKB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 276474   

TargetMannosyl-oligosaccharide glucosidase(Human)
The Rockefeller University; Memorial Sloan-Kettering Cancer Center

US Patent
LigandChemical structure of BindingDB Monomer ID 276474BDBM276474(US12522603, Compound TDI-005397)
Affinity DataIC50: 352nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2026
Entry Details US Patent

TargetCyclic GMP-AMP synthase(Human)
Ventus Therapeutics

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 276474BDBM276474(US12522603, Compound TDI-005397)
Affinity DataIC50: 440nMAssay Description:Inhibition of LRRK2 (unknown origin) phosphorylation by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed