BDBM276536 US12522616, Compound WX005

SMILES Cc1cnc(Nc2ccnn2C)nc1-c1nc2c(s1)C(C)(C)N(Cc1cccc(Cl)c1)C2=O

InChI Key InChIKey=PONUSVFCPXPCCD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 276536   

TargetMitogen-activated protein kinase 1(Human)
D3 Bio (Wuxi)

US Patent
LigandChemical structure of BindingDB Monomer ID 276536BDBM276536(US12522616, Compound WX005)
Affinity DataIC50: 0.0500nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2026
Entry Details
US Patent