BDBM276757 2-(5-((3-ethoxypyridin- 2-yl)oxy)pyridin-3-yl)- N-(2-methyl-1-(methyl- sulfonyl)propan-2-yl) pyrimidine-5-carboxamide::US10071992, Example 3.6

SMILES CCOc1cccnc1Oc1cncc(c1)-c1ncc(cn1)C(=O)NC(C)(C)S(C)(=O)=O

InChI Key InChIKey=KHXPARUTHKQJQB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 276757   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM276757(2-(5-((3-ethoxypyridin- 2-yl)oxy)pyridin-3-yl)- N-...)
Affinity DataIC50:  35.4nMpH: 7.4 T: 2°CAssay Description:For determination of IC50 values, the reactions were carried out in 384-well white Polyplates (Perkin Elmer) in a total volume of 20 μL. To 1 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent