BDBM277129 4-(5-chloropyridin-2-yl)-7-{[1- (difluoromethyl)-1H-pyrazol-5-yl]methyl}- 5,6,7,8-tetrahydro-1,7-naphthyridine-2- carboxamide::US10072003, Example 2-22

SMILES NC(=O)c1cc(-c2ccc(Cl)cn2)c2CCN(Cc3ccnn3C(F)F)Cc2n1

InChI Key InChIKey=QVBLDWYKCDCGGR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 277129   

TargetMetabotropic glutamate receptor 2(Human)
TBA

US Patent
LigandChemical structure of BindingDB Monomer ID 277129BDBM277129(US10072003, Example 2-22 | 4-(5-chloropyridin-2-yl...)
Affinity DataIC50: 1.94E+4nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
Entry Details
US Patent