BDBM278083 2-(((3R,4S)-3-fluoro-1-(2-hydroxyacetyl)piperidin-4-yl)oxy)-5-(4-((4-(1-(oxetan-3-yl)piperidin-4-yl)phenyl)amino)-1,3,5-triazin-2-yl)benzonitrile::US10040781, Example 305::US10253019, Example 305
SMILES OCC(=O)N1CC[C@H](Oc2ccc(cc2C#N)-c2ncnc(Nc3ccc(cc3)C3CCN(CC3)C3COC3)n2)[C@H](F)C1
InChI Key InChIKey=XXJDZHFAASXZSR-IAPPQJPRSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 278083
Affinity DataIC50: 2.00E+3nMpH: 7.0Assay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMpH: 7.0Assay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
Affinity DataIC50: 292nMAssay Description:Enzymatic activity of hJAK2 was measured using a LANCE homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that monitors...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
Affinity DataIC50: <1nMAssay Description:Enzymatic activity of IKKε and TBK1 was measured using a homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that m...More data for this Ligand-Target Pair
Affinity DataIC50: 2.92E+5nMpH: 7.5Assay Description:Enzymatic activity of hJAK2 was measured using a LANCE homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay that monitors...More data for this Ligand-Target Pair