BDBM279788 US10035804, Example 59

SMILES Cn1cc(cn1)C(=O)N1CC2(C1)CCN(CC2)c1cncc(c1)N1C(=O)c2ccc(Cl)cc2C1(C)C

InChI Key InChIKey=OGEMDUBGJQWNLM-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 279788   

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM279788(US10035804, Example 59)
Affinity DataEC50:  0.00100nMAssay Description:Herein we identified the use of the G-402 cell line as a host cell to ectopically express (transiently or stably) enzymes of the CYP11 family. Specif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM279788(US10035804, Example 59)
Affinity DataEC50:  0.819nMAssay Description:Herein we identified the use of the G-402 cell line as a host cell to ectopically express (transiently or stably) enzymes of the CYP11 family. Specif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2018
Entry Details
US Patent