BDBM280649 US10030020, Example 194::US10781211, Example 194

SMILES OC(=O)C1CCN(Cc2cc(Cl)cc(CN3CCCC33CCN(CC3)C(=O)OC(C(F)(F)F)C(F)(F)F)c2)CC1

InChI Key InChIKey=BOMOQKALVHDSEY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 280649   

TargetMonoglyceride lipase(Human)
Abide Therapeutics

US Patent
LigandPNGBDBM280649(US10030020, Example 194 | US10781211, Example 194)
Affinity DataIC50: 100nMT: 2°CAssay Description:Proteomes (human prefrontal cortex or cell membrane fractions) (50 μL, 1.0-2.0 mg/mL total protein concentration) were preincubated with varying...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2018
Entry Details
US Patent

TargetMonoglyceride lipase(Human)
Abide Therapeutics

US Patent
LigandPNGBDBM280649(US10030020, Example 194 | US10781211, Example 194)
Affinity DataIC50: 100nMAssay Description:Human: Proteomes (human prefrontal cortex or cell membrane fractions) (50 μL, 1.0-2.0 mg/mL total protein concentration) were preincubated with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2021
Entry Details
US Patent