BDBM281479 US10022387, Example 4::US10022387, Example 5::US10596184, Example 5::US9586949, Example 5

SMILES COc1cncc(c1)-c1ccc2nc(oc2c1)-c1cc2ccccc2[nH]1

InChI Key InChIKey=FTSBZIUYXXEART-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 281479   

LigandPNGBDBM281479(US10022387, Example 4 | US10022387, Example 5 | US...)
Affinity DataIC50: <250nMpH: 6.7 T: 25°CAssay Description:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM281479(US10022387, Example 4 | US10022387, Example 5 | US...)
Affinity DataIC50: <1.00E+3nMpH: 6.7 T: 25°CAssay Description:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM281479(US10022387, Example 4 | US10022387, Example 5 | US...)
Affinity DataIC50: <250nMpH: 6.7 T: 25°CAssay Description:γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM281479(US10022387, Example 4 | US10022387, Example 5 | US...)
Affinity DataIC50: <1.00E+3nMAssay Description:PI3Kdelta: The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM281479(US10022387, Example 4 | US10022387, Example 5 | US...)
Affinity DataIC50: <250nMpH: 6.7 T: 25°CAssay Description:γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM281479(US10022387, Example 4 | US10022387, Example 5 | US...)
Affinity DataIC50: <1.00E+3nMpH: 6.7 T: 25°CAssay Description:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM281479(US10022387, Example 4 | US10022387, Example 5 | US...)
Affinity DataIC50: <250nMAssay Description:PI3K-gamma:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM281479(US10022387, Example 4 | US10022387, Example 5 | US...)
Affinity DataIC50: <5.00E+3nMpH: 6.7 T: 25°CAssay Description:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). Lipid kinas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent