BDBM281629 US10022461, Compound 98

SMILES c1cc2ccn(-c3ccc(-c4ccn[nH]4)cn3)c2cn1

InChI Key InChIKey=VLGYZUWTASAXOK-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 281629   

TargetMicrotubule-associated protein tau(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 281629BDBM281629(US10022461, Compound 98)
Affinity DataKi:  1.13nM ΔG°:  -12.2kcal/molepH: 7.4 T: 2°CAssay Description:For displacement tau binding assay, unlabeled test compounds were dissolved in DMSO at 1 mM. Dilutions of tests compounds to various concentrations w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2018
Entry Details
US Patent