BDBM283117 (R)-(6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepin-4-yl)methyl sulfamate ::US9884874, Compound 8

SMILES COc1ccc-2c(c1)C(=N[C@@H](COS(N)(=O)=O)c1nnc(C)n-21)c1ccc(Cl)cc1

InChI Key InChIKey=TZCNSPOGRISYSL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 283117   

TargetBromodomain-containing protein 4(Human)
Kainos Medicine

US Patent
LigandPNGBDBM283117((R)-(6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-benz...)
Affinity DataIC50: 220nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent