BDBM283123 (R)-(6-(4-chlorophenyl)-8-((2-hydroxyethyl)carbamoyl)-1-methyl-4H-benzo[f][1,2,4]triazolo[4,3-a][1,4]diazepin-4-yl)methyl methanesulfonate ::US9884874, Compound 14

SMILES Cc1nnc2[C@H](CO[Si](C)(C)C(C)(C)C)N=C(c3ccc(Cl)cc3)c3cc(\C=C\c4ccccc4)ccc3-n12

InChI Key InChIKey=XYJINFFGIHFIPF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 283123   

TargetBromodomain-containing protein 4(Human)
Kainos Medicine

US Patent
LigandPNGBDBM283123((R)-(6-(4-chlorophenyl)-8-((2-hydroxyethyl)carbamo...)
Affinity DataIC50: 380nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent