BDBM283126 (R)-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)methyl dimethylsulfamate ::US9884874, Compound 17

SMILES CN(C)S(=O)(=O)OC[C@@H]1N=C(c2c(C)c(C)sc2-n2c(C)nnc12)c1ccc(Cl)cc1

InChI Key InChIKey=DWOOIAOGOFEGIJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 283126   

TargetBromodomain-containing protein 4(Human)
Kainos Medicine

US Patent
LigandPNGBDBM283126((R)-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[...)
Affinity DataIC50: 900nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent