BDBM28345 1-[2-(2-chloro-10H-phenothiazin-10-yl)-2-oxoethyl]azepan-1-ium::ZINC04866531, 4

SMILES Clc1ccc2Sc3ccccc3N(C(=O)C[NH+]3CCCCCC3)c2c1

InChI Key InChIKey=HIIMHGSUGVDCIA-UHFFFAOYSA-O

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28345   

TargetTrypanothione reductase(Trypanosoma brucei brucei)
University of Alberta

LigandPNGBDBM28345(1-[2-(2-chloro-10H-phenothiazin-10-yl)-2-oxoethyl]...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Alberta

LigandPNGBDBM28345(1-[2-(2-chloro-10H-phenothiazin-10-yl)-2-oxoethyl]...)
Affinity DataIC50:  7.87E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed