BDBM28354 2-{6-methyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl}-N-[2-(phenylsulfanyl)phenyl]acetamide::ZINC2628155, 23

SMILES CC1CCCCC11NC(=O)N(CC(=O)Nc2ccccc2Sc2ccccc2)C1=O

InChI Key InChIKey=HAWMHBRUYTWVQD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28354   

TargetTrypanothione reductase(Trypanosoma brucei brucei)
University of Alberta

LigandPNGBDBM28354(2-{6-methyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-y...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypanothione reductase(Trypanosoma cruzi)
University of Alberta

LigandPNGBDBM28354(2-{6-methyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-y...)
Affinity DataIC50:  8.44E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed