BDBM28356 (3R)-1-methyl-3-[(10R)-9-oxa-2-thiatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-10-ylmethyl]piperidin-1-ium::ZINC04128838, 25

SMILES C[NH+]1CCC[C@H](C[C@H]2Oc3ccccc3Sc3ccccc23)C1

InChI Key InChIKey=ZOXQYFLPDQGMDX-CRAIPNDOSA-O

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28356   

TargetTrypanothione reductase(Trypanosoma brucei brucei)
University of Alberta

LigandPNGBDBM28356((3R)-1-methyl-3-[(10R)-9-oxa-2-thiatricyclo[9.4.0....)
Affinity DataIC50:  1.46E+4nMAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTrypanothione reductase(Trypanosoma cruzi)
University of Alberta

LigandPNGBDBM28356((3R)-1-methyl-3-[(10R)-9-oxa-2-thiatricyclo[9.4.0....)
Affinity DataIC50:  1.15E+4nMpH: 7.5 T: 22°CAssay Description:Inhibition of TryR was carried out in 96-well plates using a Biotek Precision 2000 automated liquid handler. Reaction was initiated by addition of NA...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed