BDBM283805 N-(4-(((2S,3S)-3-fluoroazetidin-2-yl)methyl)phenyl)-2-(trifluoromethyl)pyrimidine-5-carboxamide::US10023559, Example 130

SMILES F[C@H]1CN[C@H]1Cc1ccc(NC(=O)c2cnc(nc2)C(F)(F)F)cc1

InChI Key InChIKey=ACKWAPUNQGIUMO-UHFFFAOYSA-N

Data  1 KI  1 Other

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 283805   

TargetTrace amine-associated receptor 1(Rat)
Hoffmann-La Roche

US Patent
LigandPNGBDBM283805(N-(4-(((2S,3S)-3-fluoroazetidin-2-yl)methyl)phenyl...)
Affinity DataKi:  16nMpH: 7.4Assay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2019
Entry Details
US Patent

TargetTrace amine-associated receptor 1(Mouse)
Hoffmann-La Roche

US Patent
LigandPNGBDBM283805(N-(4-(((2S,3S)-3-fluoroazetidin-2-yl)methyl)phenyl...)
Affinity DatapH: 7.4Assay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2019
Entry Details
US Patent