BDBM2846 (3-chloro-5-{1-[3-chloro-5-(hydroxymethyl)-4-methoxyphenyl]-6-(1,3-dioxolan-2-yl)oct-1-en-1-yl}-2-methoxyphenyl)methanol::3,3-Dichloro-5,5-dihydroxymethyl-4,4-dimethoxy-1,1-diphenyl-5-(2-ethyl-(1,3)-dioxolan-2-yl)-1-pentene::Alkenyldiarylmethane (ADAM) 20c

SMILES CCC(CCCC=C(c1cc(Cl)c(OC)c(CO)c1)c1cc(Cl)c(OC)c(CO)c1)C1OCCO1

InChI Key InChIKey=JRPXKCKGZGVUMR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2846   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Purdue University

LigandPNGBDBM2846((3-chloro-5-{1-[3-chloro-5-(hydroxymethyl)-4-metho...)
Affinity DataIC50: 3.20E+3nMpH: 7.9Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Purdue University

LigandPNGBDBM2846((3-chloro-5-{1-[3-chloro-5-(hydroxymethyl)-4-metho...)
Affinity DataIC50: 3.16E+4nMpH: 7.9Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2005
Entry Details Article
PubMed