BDBM284925 1-(4-amino-5-(trifluoromethyl) pyrrolo[2,1-f][1,2,4]triazin-7-yl)-N,N- dimethylpiperidine-3-carboxamide::US10023576, Example 117

SMILES CN(C)C(=O)C1CCCN(C1)c1cc(c2c(N)ncnn12)C(F)(F)F

InChI Key InChIKey=NNNGINYONCTMLE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 284925   

LigandChemical structure of BindingDB Monomer ID 284925BDBM284925(US10023576, Example 117 | 1-(4-amino-5-(trifluorom...)
Affinity DataIC50: 847nMpH: 7.5 T: 2°CAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent