BDBM28499 (3R,5S)-5-[2-(4-{[4-(pyridin-2-ylsulfanyl)phenyl]amino}thieno[3,2-d]pyrimidin-6-yl)ethynyl]pyrrolidin-3-yl morpholine-4-carboxylate::alkynyl thienopyrimidine, 15k

SMILES O=C(O[C@H]1CN[C@@H](C1)C#Cc1cc2ncnc(Nc3ccc(Sc4ccccn4)cc3)c2s1)N1CCOCC1

InChI Key InChIKey=WCDMWNJUWOHGEY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28499   

LigandChemical structure of BindingDB Monomer ID 28499BDBM28499((3R,5S)-5-[2-(4-{[4-(pyridin-2-ylsulfanyl)phenyl]a...)
Affinity DataIC50: 220nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 28499BDBM28499((3R,5S)-5-[2-(4-{[4-(pyridin-2-ylsulfanyl)phenyl]a...)
Affinity DataIC50: 1.65E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed