BDBM28503 (3R,5S)-5-{2-[4-({1-[(2,5-difluorophenyl)methyl]-1H-indazol-5-yl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrrolidin-3-yl morpholine-4-carboxylate::alkynyl thienopyrimidine, 15o

SMILES Fc1ccc(F)c(Cn2ncc3cc(Nc4ncnc5cc(sc45)C#C[C@@H]4C[C@H](CN4)OC(=O)N4CCOCC4)ccc23)c1

InChI Key InChIKey=HRADRJGXRLBLGD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28503   

LigandPNGBDBM28503((3R,5S)-5-{2-[4-({1-[(2,5-difluorophenyl)methyl]-1...)
Affinity DataIC50: 33nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28503((3R,5S)-5-{2-[4-({1-[(2,5-difluorophenyl)methyl]-1...)
Affinity DataIC50: 35nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed