BDBM28505 (3R,5S)-5-{2-[4-({1-[(3-fluorobenzene)sulfonyl]-1H-indazol-5-yl}amino)thieno[3,2-d]pyrimidin-6-yl]ethynyl}pyrrolidin-3-yl morpholine-4-carboxylate::alkynyl thienopyrimidine, 15q

SMILES Fc1cccc(c1)S(=O)(=O)n1ncc2cc(Nc3ncnc4cc(sc34)C#C[C@@H]3C[C@H](CN3)OC(=O)N3CCOCC3)ccc12

InChI Key InChIKey=DNGKMKTZKCGWMO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28505   

LigandPNGBDBM28505((3R,5S)-5-{2-[4-({1-[(3-fluorobenzene)sulfonyl]-1H...)
Affinity DataIC50: 85nMAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
LigandPNGBDBM28505((3R,5S)-5-{2-[4-({1-[(3-fluorobenzene)sulfonyl]-1H...)
Affinity DataIC50: 230nMpH: 7.5 T: 2°CAssay Description:Assays were performed in 96-well polystyrene round-bottomed plates in reaction buffer containing biotinylated substrate and purified kinase in the pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed