BDBM285374 5-[2-(cyclopropylmethylamino)-5- methylsulfonylphenyl]-1-ethyl-3- methylpyridin-2-one::BDBM486218::US10023592, Example 428

SMILES CCn1cc(cc(C)c1=O)-c1cc(ccc1NCC1CC1)S(C)(=O)=O

InChI Key InChIKey=CLEKCLQDYNETIQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 285374   

TargetBromodomain-containing protein 4(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM285374(US10023592, Example 428 | BDBM486218 | 5-[2-(cyclo...)
Affinity DataIC50: 500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/20/2021
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM285374(US10023592, Example 428 | BDBM486218 | 5-[2-(cyclo...)
Affinity DataIC50: 500nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent