BDBM28549 4-N,8-N,12-trimethyl-5-thia-3,7,10,12-tetraazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),3,7,10-pentaene-4,8-diamine::thiazole-based tricyclic inhibitor, 23a

SMILES CNc1nc2c(nc(NC)c3ncn(C)c23)s1

InChI Key InChIKey=JQRXDQHWUPGSCK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28549   

LigandPNGBDBM28549(4-N,8-N,12-trimethyl-5-thia-3,7,10,12-tetraazatric...)
Affinity DataIC50:  3.40E+3nMT: 25°CAssay Description:Assays measuring the enzyme catalyzed phosphorylation of GST-I-kappa-B-alpha were performed by adding enzyme at room temperature to substrate solutio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM28549(4-N,8-N,12-trimethyl-5-thia-3,7,10,12-tetraazatric...)
Affinity DataIC50:  920nMpH: 7.5 T: 22°CAssay Description:Assays measuring the enzyme catalyzed phosphorylation of GST-I-kappa-B-alpha were performed by adding enzyme at room temperature to substrate solutio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed