BDBM285551 4-[2-(azetidin-1-ylcarbonyl)imidazo[1,2-b]pyridazin-3-yl]-2,5-difluorobenzonitrile::US10077269, Example 24::US10669279, Example 24::US9598421, Example 24

SMILES Fc1cc(-c2c(nc3cccnn23)C(=O)N2CCC2)c(F)cc1C#N

InChI Key InChIKey=GLYPDLWNQYDRTQ-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 285551   

LigandPNGBDBM285551(4-[2-(azetidin-1-ylcarbonyl)imidazo[1,2-b]pyridazi...)
Affinity DataIC50:  5.04nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285551(4-[2-(azetidin-1-ylcarbonyl)imidazo[1,2-b]pyridazi...)
Affinity DataIC50:  19.1nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285551(4-[2-(azetidin-1-ylcarbonyl)imidazo[1,2-b]pyridazi...)
Affinity DataIC50:  59.7nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285551(4-[2-(azetidin-1-ylcarbonyl)imidazo[1,2-b]pyridazi...)
Affinity DataIC50: >2.15E+3nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285551(4-[2-(azetidin-1-ylcarbonyl)imidazo[1,2-b]pyridazi...)
Affinity DataIC50:  5.04nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285551(4-[2-(azetidin-1-ylcarbonyl)imidazo[1,2-b]pyridazi...)
Affinity DataIC50: >2.15E+3nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285551(4-[2-(azetidin-1-ylcarbonyl)imidazo[1,2-b]pyridazi...)
Affinity DataIC50:  59.7nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285551(4-[2-(azetidin-1-ylcarbonyl)imidazo[1,2-b]pyridazi...)
Affinity DataIC50: >2.15E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285551(4-[2-(azetidin-1-ylcarbonyl)imidazo[1,2-b]pyridazi...)
Affinity DataIC50:  5.04nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285551(4-[2-(azetidin-1-ylcarbonyl)imidazo[1,2-b]pyridazi...)
Affinity DataIC50:  19.1nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285551(4-[2-(azetidin-1-ylcarbonyl)imidazo[1,2-b]pyridazi...)
Affinity DataIC50:  59.7nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


LigandPNGBDBM285551(4-[2-(azetidin-1-ylcarbonyl)imidazo[1,2-b]pyridazi...)
Affinity DataIC50:  19.1nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent