BDBM285582 US10077269, Example 55::US10669279, Example 55::US9598421, Example 55::azetidin-1-yl[3-(3-fluoro-4-methoxyphenyl)imidazo[1,2-b]pyridazin-2-yl]methanone

SMILES COc1ccc(cc1F)-c1c(nc2cccnn12)C(=O)N1CCC1

InChI Key InChIKey=GGBSVVWNJGUOLN-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 285582   

LigandChemical structure of BindingDB Monomer ID 285582BDBM285582(US10077269, Example 55 | azetidin-1-yl[3-(3-fluoro...)
Affinity DataIC50: 176nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 285582BDBM285582(US10077269, Example 55 | azetidin-1-yl[3-(3-fluoro...)
Affinity DataIC50: 176nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 285582BDBM285582(US10077269, Example 55 | azetidin-1-yl[3-(3-fluoro...)
Affinity DataIC50: 176nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 285582BDBM285582(US10077269, Example 55 | azetidin-1-yl[3-(3-fluoro...)
Affinity DataIC50: 200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 285582BDBM285582(US10077269, Example 55 | azetidin-1-yl[3-(3-fluoro...)
Affinity DataIC50: 200nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 285582BDBM285582(US10077269, Example 55 | azetidin-1-yl[3-(3-fluoro...)
Affinity DataIC50: 200nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 285582BDBM285582(US10077269, Example 55 | azetidin-1-yl[3-(3-fluoro...)
Affinity DataIC50: 1.55E+3nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 285582BDBM285582(US10077269, Example 55 | azetidin-1-yl[3-(3-fluoro...)
Affinity DataIC50: 1.55E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 285582BDBM285582(US10077269, Example 55 | azetidin-1-yl[3-(3-fluoro...)
Affinity DataIC50: 1.55E+3nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 285582BDBM285582(US10077269, Example 55 | azetidin-1-yl[3-(3-fluoro...)
Affinity DataIC50: 2.09E+4nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 285582BDBM285582(US10077269, Example 55 | azetidin-1-yl[3-(3-fluoro...)
Affinity DataIC50: 2.09E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 285582BDBM285582(US10077269, Example 55 | azetidin-1-yl[3-(3-fluoro...)
Affinity DataIC50: 2.09E+4nMAssay Description:Human PDE4A3 coding sequence (amino acids 2 to 825 from the sequence with accession number NP_001104779) was cloned into the baculovirus expression v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
US Patent